Counterattacking Diabetes with an Ancient Gene Mutation


Scientists from the University College London or ULC recently uncovered an aged deviation that can scatter within individuals. Experts believe that this old form of variation might shield people from high blood sugar difficulties and cases of diabetes.

A Gene’s History

In the past, the gene’s previous form was beneficial for early humans as the protein it provides maintained the glucose transporters securely inside muscles and fats, which resulted for the body’s sugar levels to remain uplifted.

By the time humans learned how to farm and cook, the sugar intake gradually increased at the same time. It became favorable for the newer modification. The variant inputs a particular type of protein that is less efficient for preserving the transporters inside the tissues and lipids.

The Uncovering

The specialists found the said mutation during one of their studies. They were examining CLTCL 1 – a gene that is deeply associated with the process of removing sugar from a person’s bloodstream – at the time when they discovered the mutant gene.

Experts also believe that the gene’s mutated figure became prevalent back then when humans learned the concept of cooking and cultivation.

According to them, they have compared DNAs of various life forms and humans to trace the CLTCL1 gene and found that ever since the evolution of jawed vertebrates, numerous species lost the gene as it deemed unimportant for all organisms.

The case is entirely different for humans; their bodies are carriers of the gene’s various forms rather than just retaining it. It is perfectly in line with the humans’ present diet, which is high in carbs for it produces a more substantial amount of sugar that replenishes stamina for the body.

Most importantly, the scientists stated that it is crucial for humans to know the gene variant that they have in their body for it will enlighten them on the possibilities and dangers of having a type two diabetes.